PQ-IM-SEM-003·Sequence-Related ImpurityMade to Order

Des-Thr Semaglutide Deletion Impurity Reference Material

Reference standard for Thr-deletion impurity identification in Semaglutide analytical methods.

PARENT PEPTIDE

Semaglutide

MATERIAL TYPE

Sequence-Related Impurity

TARGET PURITY

≥90% (HPLC)

EVIDENCE STATUS

Peer-Reviewed

Made to Order

QUANTITY

1 mg5 mgCustom

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DOCUMENTATION

HPLC purity

LC-MS mass confirmation

Certificate of Analysis

QUALITY CONTEXT

Why This Record Matters

Threonine deletion impurities arise from synthesis inefficiencies and are relevant to Semaglutide impurity profiling.

POTENTIAL ORIGIN

Incomplete coupling at Thr residue positions during solid-phase peptide synthesis.

Analytical Data Package

HPLC Purity Data

LC-MS Mass Confirmation

MS/MS Fragmentation

Certificate of Analysis

PEPTIQORE APPROACH

Quality Record

Supporting Evidence

Analytical Data

Related Impurities

Analytical Method Context

Experimental Support

TRADITIONAL SUPPLIER

Product → CoA

IMPURITY CLASSIFICATION

Sequence-Related Impurity

EVIDENCE STATUS

Peer-Reviewed

PARENT PEPTIDE

Semaglutide Quality Hub →

RELATED ANALYTICAL MATERIALS

PQ-RM-SEM-001Available

Semaglutide Reference Material

Required for HPLC system suitability, method validation, and as a reference standard for impurity quantification relative to the parent compound.

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PQ-IM-SEM-001Made to Order

Des-His¹ Semaglutide

Used as a reference standard for identification and quantification of N-terminal deletion impurities in Semaglutide drug substance and drug product.

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PQ-IM-SEM-002Made to Order

Des-Gly Semaglutide

Reference standard for Gly-deletion impurity identification and quantification in Semaglutide quality control.

View record

CUSTOM DEVELOPMENT

Can't Find Your Impurity?

PeptiQore supports custom development of peptide-related impurities, sequence variants and degradation materials.

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